The impact to the story would be – had Hughes didn’t get killed in episode 10.
Yes this is spoiler. And no, I don’t care since everyone and their pet should’ve known about this years ago.
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Oh and moar spoiler: the things he realized will be dicovered in faaaaaaar away in the manga, about 10 volumes apart (hence my lateness of realizing it – or actually it’s pretty normal for me since I’ve forgotten about this chapter)
He makes me want human transmutation to be possible 🙂